Testing performed: I used a Particle Xenon with a HDA1334 I2S DAC.
I played a variety of mono 16-bit samples at 11025 and 22050Hz nominal
bit rates. With this setup, all the 11025Hz samples sound good.
I tested play, pause, and loop functionality.
During some runs with 22050Hz samples, there were glitches. However,
these may have only occurred during runs where I had set breakpoints
and watchpoints in gdb.
I also tested with a MAX98357A I2S amplifier. On this device, everything
sounded "scratchy". I was powering it from 5V and the 5V rail seemed
steady, so I don't have an explanation for this. However, I haven't
tried it with a SAMD board.