As part of this patch the MICROPY_HW_LED_OTYPE setting is removed because it is now unused (all boards anyway had this as OUTPUT_PP).
UART1 can be used even if the switch is enabled. The schematics for this board make I2C1 available on PB8/PB9, even though it can also be mapped to PB6/PB7. See #2396 and #2427.