You can either set it once up front, or set variable_frequency on custruction to
indicate that the frequency must be able to change. This informs whether a timer
can be shared amongst pins.
This also adds persistent clock calibration on atmel-samd. Once the device has
synced its clock frequency over USB it will remember that config value until USB
is used again. This helps ensure the clock frequency is similar on and off USB.
Lastly, this also corrects time.sleep() when on USB by correcting the tick counter.
Everything works fine without USB being plugged in but faults (I think) when USB is plugged in. This is switched away from the USB code from the bootloader onto the USB code thats generated by Atmel Studio using the high level classes from ASF.