diff --git a/ports/stm32/stm32_it.c b/ports/stm32/stm32_it.c
index 7363e26e89..50fd56ecae 100644
--- a/ports/stm32/stm32_it.c
+++ b/ports/stm32/stm32_it.c
@@ -1015,6 +1015,14 @@ void UART10_IRQHandler(void) {
 }
 #endif
 
+#if defined(USART10)
+void USART10_IRQHandler(void) {
+    IRQ_ENTER(USART10_IRQn);
+    uart_irq_handler(10);
+    IRQ_EXIT(USART10_IRQn);
+}
+#endif
+
 #endif
 
 #if defined(LPUART1)
diff --git a/ports/stm32/uart.c b/ports/stm32/uart.c
index 7a2a3a9580..1823596df1 100644
--- a/ports/stm32/uart.c
+++ b/ports/stm32/uart.c
@@ -491,9 +491,15 @@ bool uart_init(pyb_uart_obj_t *uart_obj,
         #if defined(MICROPY_HW_UART10_TX) && defined(MICROPY_HW_UART10_RX)
         case PYB_UART_10:
             uart_unit = 10;
+            #if defined(UART10)
             UARTx = UART10;
             irqn = UART10_IRQn;
             __HAL_RCC_UART10_CLK_ENABLE();
+            #else
+            UARTx = USART10;
+            irqn = USART10_IRQn;
+            __HAL_RCC_USART10_CLK_ENABLE();
+            #endif
             pins[0] = MICROPY_HW_UART10_TX;
             pins[1] = MICROPY_HW_UART10_RX;
             break;
@@ -771,6 +777,13 @@ void uart_deinit(pyb_uart_obj_t *self) {
         __HAL_RCC_UART10_RELEASE_RESET();
         __HAL_RCC_UART10_CLK_DISABLE();
     #endif
+    #if defined(USART10)
+    } else if (self->uart_id == 10) {
+        HAL_NVIC_DisableIRQ(USART10_IRQn);
+        __HAL_RCC_USART10_FORCE_RESET();
+        __HAL_RCC_USART10_RELEASE_RESET();
+        __HAL_RCC_USART10_CLK_DISABLE();
+    #endif
     #if defined(LPUART1)
     } else if (self->uart_id == PYB_LPUART_1) {
         #if defined(STM32G0)
@@ -886,7 +899,7 @@ uint32_t uart_get_source_freq(pyb_uart_obj_t *self) {
         #if defined(UART9)
         || self->uart_id == 9
         #endif
-        #if defined(UART10)
+        #if defined(UART10) || defined(USART10)
         || self->uart_id == 10
         #endif
         ) {