diff --git a/stmhal/boards/STM32F429DISC/mpconfigboard.h b/stmhal/boards/STM32F429DISC/mpconfigboard.h
index dc4059d030..33dd507d51 100644
--- a/stmhal/boards/STM32F429DISC/mpconfigboard.h
+++ b/stmhal/boards/STM32F429DISC/mpconfigboard.h
@@ -1,3 +1,5 @@
+#include STM32_HAL_H
+
 #define MICROPY_HW_BOARD_NAME       "F429I-DISCO"
 #define MICROPY_HW_MCU_NAME         "STM32F429"
 
@@ -29,6 +31,32 @@
 #define MICROPY_HW_I2C1_SCL (pin_A8)
 #define MICROPY_HW_I2C1_SDA (pin_C9)
 
+// SPI busses
+//#define MICROPY_HW_SPI1_NSS     (pin_A4)
+//#define MICROPY_HW_SPI1_SCK     (pin_A5)
+//#define MICROPY_HW_SPI1_MISO    (pin_A6)
+//#define MICROPY_HW_SPI1_MOSI    (pin_A7)
+#if defined(USE_USB_HS_IN_FS)
+// The HS USB uses B14 & B15 for D- and D+
+#else
+#define MICROPY_HW_SPI2_NSS  (pin_B12)
+#define MICROPY_HW_SPI2_SCK  (pin_B13)
+#define MICROPY_HW_SPI2_MISO (pin_B14)
+#define MICROPY_HW_SPI2_MOSI (pin_B15)
+#endif
+//#define MICROPY_HW_SPI4_NSS     (pin_E11)
+//#define MICROPY_HW_SPI4_SCK     (pin_E12)
+//#define MICROPY_HW_SPI4_MISO    (pin_E13)
+//#define MICROPY_HW_SPI4_MOSI    (pin_E14)
+#define MICROPY_HW_SPI5_NSS     (pin_F6)
+#define MICROPY_HW_SPI5_SCK     (pin_F7)
+#define MICROPY_HW_SPI5_MISO    (pin_F8)
+#define MICROPY_HW_SPI5_MOSI    (pin_F9)
+//#define MICROPY_HW_SPI6_NSS     (pin_G8)
+//#define MICROPY_HW_SPI6_SCK     (pin_G13)
+//#define MICROPY_HW_SPI6_MISO    (pin_G12)
+//#define MICROPY_HW_SPI6_MOSI    (pin_G14)
+
 // USRSW is pulled low. Pressing the button makes the input go high.
 #define MICROPY_HW_USRSW_PIN        (pin_A0)
 #define MICROPY_HW_USRSW_PULL       (GPIO_NOPULL)
diff --git a/stmhal/dma.h b/stmhal/dma.h
index 0e751757fd..9561d1b529 100644
--- a/stmhal/dma.h
+++ b/stmhal/dma.h
@@ -74,12 +74,30 @@
 #define DMA_STREAM_SPI1_RX      DMA2_Stream2
 #define DMA_CHANNEL_SPI1_RX                     DMA_CHANNEL_3
 
+#define DMA_STREAM_SPI5_RX      DMA2_Stream3
+#define DMA_CHANNEL_SPI5_RX                     DMA_CHANNEL_2
+
 #define DMA_STREAM_SDIO_RX      DMA2_Stream3
 #define DMA_CHANNEL_SDIO_RX                     DMA_CHANNEL_4
 
+#define DMA_STREAM_SPI4_RX      DMA2_Stream3
+#define DMA_CHANNEL_SPI4_RX                     DMA_CHANNEL_5
+
+#define DMA_STREAM_SPI5_TX      DMA2_Stream4
+#define DMA_CHANNEL_SPI5_TX                     DMA_CHANNEL_2
+
+#define DMA_STREAM_SPI4_TX      DMA2_Stream4
+#define DMA_CHANNEL_SPI4_TX                     DMA_CHANNEL_5
+
+#define DMA_STREAM_SPI6_TX      DMA2_Stream5
+#define DMA_CHANNEL_SPI6_TX                     DMA_CHANNEL_1
+
 #define DMA_STREAM_SPI1_TX      DMA2_Stream5
 #define DMA_CHANNEL_SPI1_TX                     DMA_CHANNEL_3
 
+#define DMA_STREAM_SPI6_RX      DMA2_Stream6
+#define DMA_CHANNEL_SPI6_RX                     DMA_CHANNEL_1
+
 #define DMA_STREAM_SDIO_TX      DMA2_Stream6
 #define DMA_CHANNEL_SDIO_TX                     DMA_CHANNEL_4
 
diff --git a/stmhal/spi.c b/stmhal/spi.c
index f2036aadd7..d9bc7ec42f 100644
--- a/stmhal/spi.c
+++ b/stmhal/spi.c
@@ -68,6 +68,12 @@
 // SPI2_RX: DMA1_Stream3.CHANNEL_0
 // SPI3_TX: DMA1_Stream5.CHANNEL_0 or DMA1_Stream7.CHANNEL_0
 // SPI3_RX: DMA1_Stream0.CHANNEL_0 or DMA1_Stream2.CHANNEL_0
+// SPI4_TX: DMA2_Stream4.CHANNEL_5 or DMA2_Stream1.CHANNEL_4
+// SPI4_RX: DMA2_Stream3.CHANNEL_5 or DMA2_Stream0.CHANNEL_4
+// SPI5_TX: DMA2_Stream4.CHANNEL_2 or DMA2_Stream6.CHANNEL_7
+// SPI5_RX: DMA2_Stream3.CHANNEL_2 or DMA2_Stream5.CHANNEL_7
+// SPI6_TX: DMA2_Stream5.CHANNEL_1
+// SPI6_RX: DMA2_Stream6.CHANNEL_1
 
 typedef struct _pyb_spi_obj_t {
     mp_obj_base_t base;
@@ -87,6 +93,15 @@ SPI_HandleTypeDef SPIHandle2 = {.Instance = NULL};
 #if defined(MICROPY_HW_SPI3_SCK)
 SPI_HandleTypeDef SPIHandle3 = {.Instance = NULL};
 #endif
+#if defined(MICROPY_HW_SPI4_SCK)
+SPI_HandleTypeDef SPIHandle4 = {.Instance = NULL};
+#endif
+#if defined(MICROPY_HW_SPI5_SCK)
+SPI_HandleTypeDef SPIHandle5 = {.Instance = NULL};
+#endif
+#if defined(MICROPY_HW_SPI6_SCK)
+SPI_HandleTypeDef SPIHandle6 = {.Instance = NULL};
+#endif
 
 STATIC const pyb_spi_obj_t pyb_spi_obj[] = {
     #if defined(MICROPY_HW_SPI1_SCK)
@@ -104,6 +119,21 @@ STATIC const pyb_spi_obj_t pyb_spi_obj[] = {
     #else
     {{&pyb_spi_type}, NULL, NULL, 0, NULL, 0},
     #endif
+    #if defined(MICROPY_HW_SPI4_SCK)
+    {{&pyb_spi_type}, &SPIHandle4, DMA_STREAM_SPI4_TX, DMA_CHANNEL_SPI4_TX, DMA_STREAM_SPI4_RX, DMA_CHANNEL_SPI4_RX},
+    #else
+    {{&pyb_spi_type}, NULL, NULL, 0, NULL, 0},
+    #endif
+    #if defined(MICROPY_HW_SPI5_SCK)
+    {{&pyb_spi_type}, &SPIHandle5, DMA_STREAM_SPI5_TX, DMA_CHANNEL_SPI5_TX, DMA_STREAM_SPI5_RX, DMA_CHANNEL_SPI5_RX},
+    #else
+    {{&pyb_spi_type}, NULL, NULL, 0, NULL, 0},
+    #endif
+    #if defined(MICROPY_HW_SPI6_SCK)
+    {{&pyb_spi_type}, &SPIHandle6, DMA_STREAM_SPI6_TX, DMA_CHANNEL_SPI6_TX, DMA_STREAM_SPI6_RX, DMA_CHANNEL_SPI6_RX},
+    #else
+    {{&pyb_spi_type}, NULL, NULL, 0, NULL, 0},
+    #endif
 };
 
 void spi_init0(void) {
@@ -120,6 +150,18 @@ void spi_init0(void) {
     memset(&SPIHandle3, 0, sizeof(SPI_HandleTypeDef));
     SPIHandle3.Instance = SPI3;
     #endif
+    #if defined(MICROPY_HW_SPI4_SCK)
+    memset(&SPIHandle4, 0, sizeof(SPI_HandleTypeDef));
+    SPIHandle4.Instance = SPI4;
+    #endif
+    #if defined(MICROPY_HW_SPI5_SCK)
+    memset(&SPIHandle5, 0, sizeof(SPI_HandleTypeDef));
+    SPIHandle5.Instance = SPI5;
+    #endif
+    #if defined(MICROPY_HW_SPI6_SCK)
+    memset(&SPIHandle6, 0, sizeof(SPI_HandleTypeDef));
+    SPIHandle6.Instance = SPI6;
+    #endif
 }
 
 // TODO allow to take a list of pins to use
@@ -167,6 +209,39 @@ void spi_init(SPI_HandleTypeDef *spi, bool enable_nss_pin) {
         // enable the SPI clock
         __SPI3_CLK_ENABLE();
     #endif
+    #if defined(MICROPY_HW_SPI4_SCK)
+    } else if (spi->Instance == SPI4) {
+        self = &pyb_spi_obj[3];
+        pins[0] = &MICROPY_HW_SPI4_NSS;
+        pins[1] = &MICROPY_HW_SPI4_SCK;
+        pins[2] = &MICROPY_HW_SPI4_MISO;
+        pins[3] = &MICROPY_HW_SPI4_MOSI;
+        GPIO_InitStructure.Alternate = GPIO_AF5_SPI4;
+        // enable the SPI clock
+        __SPI4_CLK_ENABLE();
+    #endif
+    #if defined(MICROPY_HW_SPI5_SCK)
+    } else if (spi->Instance == SPI5) {
+        self = &pyb_spi_obj[4];
+        pins[0] = &MICROPY_HW_SPI5_NSS;
+        pins[1] = &MICROPY_HW_SPI5_SCK;
+        pins[2] = &MICROPY_HW_SPI5_MISO;
+        pins[3] = &MICROPY_HW_SPI5_MOSI;
+        GPIO_InitStructure.Alternate = GPIO_AF5_SPI5;
+        // enable the SPI clock
+        __SPI5_CLK_ENABLE();
+    #endif
+    #if defined(MICROPY_HW_SPI6_SCK)
+    } else if (spi->Instance == SPI6) {
+        self = &pyb_spi_obj[5];
+        pins[0] = &MICROPY_HW_SPI6_NSS;
+        pins[1] = &MICROPY_HW_SPI6_SCK;
+        pins[2] = &MICROPY_HW_SPI6_MISO;
+        pins[3] = &MICROPY_HW_SPI6_MOSI;
+        GPIO_InitStructure.Alternate = GPIO_AF5_SPI6;
+        // enable the SPI clock
+        __SPI6_CLK_ENABLE();
+    #endif
     } else {
         // SPI does not exist for this board (shouldn't get here, should be checked by caller)
         return;
@@ -215,6 +290,24 @@ void spi_deinit(SPI_HandleTypeDef *spi) {
         __SPI3_RELEASE_RESET();
         __SPI3_CLK_DISABLE();
     #endif
+    #if defined(MICROPY_HW_SPI4_SCK)
+    } else if (spi->Instance == SPI4) {
+        __SPI4_FORCE_RESET();
+        __SPI4_RELEASE_RESET();
+        __SPI4_CLK_DISABLE();
+    #endif
+    #if defined(MICROPY_HW_SPI5_SCK)
+    } else if (spi->Instance == SPI5) {
+        __SPI5_FORCE_RESET();
+        __SPI5_RELEASE_RESET();
+        __SPI5_CLK_DISABLE();
+    #endif
+    #if defined(MICROPY_HW_SPI6_SCK)
+    } else if (spi->Instance == SPI6) {
+        __SPI6_FORCE_RESET();
+        __SPI6_RELEASE_RESET();
+        __SPI6_CLK_DISABLE();
+    #endif
     }
 }
 
@@ -245,10 +338,18 @@ SPI_HandleTypeDef *spi_get_handle(mp_obj_t o) {
 STATIC void pyb_spi_print(const mp_print_t *print, mp_obj_t self_in, mp_print_kind_t kind) {
     pyb_spi_obj_t *self = self_in;
 
-    uint spi_num;
-    if (self->spi->Instance == SPI1) { spi_num = 1; }
-    else if (self->spi->Instance == SPI2) { spi_num = 2; }
-    else { spi_num = 3; }
+    uint spi_num = 1; // default to SPI1
+    if (self->spi->Instance == SPI2) { spi_num = 2; }
+    else if (self->spi->Instance == SPI3) { spi_num = 3; }
+    #if defined(SPI4)
+    else if (self->spi->Instance == SPI4) { spi_num = 4; }
+    #endif
+    #if defined(SPI5)
+    else if (self->spi->Instance == SPI5) { spi_num = 5; }
+    #endif
+    #if defined(SPI6)
+    else if (self->spi->Instance == SPI6) { spi_num = 6; }
+    #endif
 
     if (self->spi->State == HAL_SPI_STATE_RESET) {
         mp_printf(print, "SPI(%u)", spi_num);
@@ -256,12 +357,12 @@ STATIC void pyb_spi_print(const mp_print_t *print, mp_obj_t self_in, mp_print_ki
         if (self->spi->Init.Mode == SPI_MODE_MASTER) {
             // compute baudrate
             uint spi_clock;
-            if (self->spi->Instance == SPI1) {
-                // SPI1 is on APB2
-                spi_clock = HAL_RCC_GetPCLK2Freq();
-            } else {
+            if (self->spi->Instance == SPI2 || self->spi->Instance == SPI3) {
                 // SPI2 and SPI3 are on APB1
                 spi_clock = HAL_RCC_GetPCLK1Freq();
+            } else {
+                // SPI1, SPI4, SPI5 and SPI6 are on APB2
+                spi_clock = HAL_RCC_GetPCLK2Freq();
             }
             uint log_prescaler = (self->spi->Init.BaudRatePrescaler >> 3) + 1;
             uint baudrate = spi_clock >> log_prescaler;
@@ -311,12 +412,12 @@ STATIC mp_obj_t pyb_spi_init_helper(const pyb_spi_obj_t *self, mp_uint_t n_args,
     if (br_prescale == 0xffffffff) {
         // prescaler not given, so select one that yields at most the requested baudrate
         mp_uint_t spi_clock;
-        if (self->spi->Instance == SPI1) {
-            // SPI1 is on APB2
-            spi_clock = HAL_RCC_GetPCLK2Freq();
-        } else {
+        if (self->spi->Instance == SPI2 || self->spi->Instance == SPI3) {
             // SPI2 and SPI3 are on APB1
             spi_clock = HAL_RCC_GetPCLK1Freq();
+        } else {
+            // SPI1, SPI4, SPI5 and SPI6 are on APB2
+            spi_clock = HAL_RCC_GetPCLK2Freq();
         }
         br_prescale = spi_clock / args[1].u_int;
     }
diff --git a/stmhal/spi.h b/stmhal/spi.h
index 9f81552525..bf9eabfcab 100644
--- a/stmhal/spi.h
+++ b/stmhal/spi.h
@@ -27,6 +27,9 @@
 extern SPI_HandleTypeDef SPIHandle1;
 extern SPI_HandleTypeDef SPIHandle2;
 extern SPI_HandleTypeDef SPIHandle3;
+extern SPI_HandleTypeDef SPIHandle4;
+extern SPI_HandleTypeDef SPIHandle5;
+extern SPI_HandleTypeDef SPIHandle6;
 extern const mp_obj_type_t pyb_spi_type;
 
 void spi_init0(void);