diff --git a/ports/atmel-samd/boards/metro_m4_airlift_lite/mpconfigboard.mk b/ports/atmel-samd/boards/metro_m4_airlift_lite/mpconfigboard.mk
index e999629c32..4895cda77b 100644
--- a/ports/atmel-samd/boards/metro_m4_airlift_lite/mpconfigboard.mk
+++ b/ports/atmel-samd/boards/metro_m4_airlift_lite/mpconfigboard.mk
@@ -6,10 +6,6 @@ USB_MANUFACTURER = "Adafruit Industries LLC"
 CHIP_VARIANT = SAMD51J19A
 CHIP_FAMILY = samd51
 
-# Support _bleio via the on-board ESP32 module.
-CIRCUITPY_BLEIO = 1
-CIRCUITPY_BLEIO_HCI = 1
-
 QSPI_FLASH_FILESYSTEM = 1
 EXTERNAL_FLASH_DEVICE_COUNT = 3
 EXTERNAL_FLASH_DEVICES = "S25FL116K, S25FL216K, GD25Q16C"
diff --git a/ports/atmel-samd/mpconfigport.mk b/ports/atmel-samd/mpconfigport.mk
index a16daf4b00..1929e146d3 100644
--- a/ports/atmel-samd/mpconfigport.mk
+++ b/ports/atmel-samd/mpconfigport.mk
@@ -37,6 +37,9 @@ ifndef CIRCUITPY_TOUCHIO_USE_NATIVE
 CIRCUITPY_TOUCHIO_USE_NATIVE = 1
 endif
 
+# No room for HCI _bleio on SAMD21.
+CIRCUITPY_BLEIO_HCI = 0
+
 CIRCUITPY_SDCARDIO ?= 0
 
 # Not enough RAM for framebuffers
diff --git a/ports/nrf/mpconfigport.mk b/ports/nrf/mpconfigport.mk
index ed689545d0..9560064fbc 100644
--- a/ports/nrf/mpconfigport.mk
+++ b/ports/nrf/mpconfigport.mk
@@ -23,6 +23,9 @@ CIRCUITPY_AUDIOCORE ?= 1
 CIRCUITPY_AUDIOMIXER ?= 1
 CIRCUITPY_AUDIOPWMIO ?= 1
 
+# Native BLEIO is not compatible with HCI _bleio.
+CIRCUITPY_BLEIO_HCI = 0
+
 CIRCUITPY_BLEIO ?= 1
 
 # No I2CPeripheral implementation
diff --git a/py/circuitpy_mpconfig.mk b/py/circuitpy_mpconfig.mk
index 91850448db..a6aabec33d 100644
--- a/py/circuitpy_mpconfig.mk
+++ b/py/circuitpy_mpconfig.mk
@@ -79,14 +79,14 @@ CFLAGS += -DCIRCUITPY_AUDIOMP3=$(CIRCUITPY_AUDIOMP3)
 CIRCUITPY_BITBANGIO ?= $(CIRCUITPY_FULL_BUILD)
 CFLAGS += -DCIRCUITPY_BITBANGIO=$(CIRCUITPY_BITBANGIO)
 
-# Explicitly enabled for boards that support _bleio.
-CIRCUITPY_BLEIO ?= 0
-CFLAGS += -DCIRCUITPY_BLEIO=$(CIRCUITPY_BLEIO)
-
 # _bleio can be supported on most any board via HCI
-CIRCUITPY_BLEIO_HCI ?= 0
+CIRCUITPY_BLEIO_HCI ?= $(CIRCUITPY_FULL_BUILD)
 CFLAGS += -DCIRCUITPY_BLEIO_HCI=$(CIRCUITPY_BLEIO_HCI)
 
+# Explicitly enabled for boards that support _bleio.
+CIRCUITPY_BLEIO ?= $(CIRCUITPY_BLEIO_HCI)
+CFLAGS += -DCIRCUITPY_BLEIO=$(CIRCUITPY_BLEIO)
+
 CIRCUITPY_BOARD ?= 1
 CFLAGS += -DCIRCUITPY_BOARD=$(CIRCUITPY_BOARD)