diff --git a/py/runtime.c b/py/runtime.c
index c255574643..4bab03b80c 100644
--- a/py/runtime.c
+++ b/py/runtime.c
@@ -1191,17 +1191,31 @@ mp_vm_return_kind_t mp_resume(mp_obj_t self_in, mp_obj_t send_value, mp_obj_t th
 
     mp_obj_t dest[3]; // Reserve slot for send() arg
 
+    // Python instance iterator protocol
     if (send_value == mp_const_none) {
         mp_load_method_maybe(self_in, MP_QSTR___next__, dest);
         if (dest[0] != MP_OBJ_NULL) {
-            *ret_val = mp_call_method_n_kw(0, 0, dest);
-            return MP_VM_RETURN_YIELD;
+            nlr_buf_t nlr;
+            if (nlr_push(&nlr) == 0) {
+                *ret_val = mp_call_method_n_kw(0, 0, dest);
+                nlr_pop();
+                return MP_VM_RETURN_YIELD;
+            } else {
+                *ret_val = nlr.ret_val;
+                return MP_VM_RETURN_EXCEPTION;
+            }
         }
     }
 
+    // Either python instance generator protocol, or native object
+    // generator protocol.
     if (send_value != MP_OBJ_NULL) {
         mp_load_method(self_in, MP_QSTR_send, dest);
         dest[2] = send_value;
+        // TODO: This should have exception wrapping like __next__ case
+        // above. Not done right away to think how to optimize native
+        // generators better, see:
+        // https://github.com/micropython/micropython/issues/2628
         *ret_val = mp_call_method_n_kw(1, 0, dest);
         return MP_VM_RETURN_YIELD;
     }