diff --git a/.github/workflows/run-tests.yml b/.github/workflows/run-tests.yml
index 76422b1c3d..71f10339f3 100644
--- a/.github/workflows/run-tests.yml
+++ b/.github/workflows/run-tests.yml
@@ -61,5 +61,5 @@ jobs:
         make -C examples/natmod/uzlib
     - name: Test native modules
       if: matrix.test == 'all'
-      run: ./run-natmodtests.py extmod/{btree*,framebuf*,uheapq*,ure*,uzlib*}.py
+      run: ./run-natmodtests.py extmod/{uheapq*,ure*,uzlib*}.py
       working-directory: tests
diff --git a/tests/run-natmodtests.py b/tests/run-natmodtests.py
index 2a0997c185..0942918d90 100755
--- a/tests/run-natmodtests.py
+++ b/tests/run-natmodtests.py
@@ -17,8 +17,6 @@ NATMOD_EXAMPLE_DIR = "../examples/natmod/"
 
 # Supported tests and their corresponding mpy module
 TEST_MAPPINGS = {
-    "btree": "btree/btree_$(ARCH).mpy",
-    "framebuf": "framebuf/framebuf_$(ARCH).mpy",
     "uheapq": "uheapq/uheapq_$(ARCH).mpy",
     "urandom": "urandom/urandom_$(ARCH).mpy",
     "ure": "ure/ure_$(ARCH).mpy",