diff --git a/ports/esp32/boards/ESP32_GENERIC_C3/mpconfigboard.h b/ports/esp32/boards/ESP32_GENERIC_C3/mpconfigboard.h
index d403e70e46..42e77ecb1a 100644
--- a/ports/esp32/boards/ESP32_GENERIC_C3/mpconfigboard.h
+++ b/ports/esp32/boards/ESP32_GENERIC_C3/mpconfigboard.h
@@ -6,3 +6,6 @@
 #define MICROPY_HW_ENABLE_SDCARD            (0)
 #define MICROPY_PY_MACHINE_DAC              (0)
 #define MICROPY_PY_MACHINE_I2S              (0)
+
+// Enable UART REPL for modules that have an external USB-UART and don't use native USB.
+#define MICROPY_HW_ENABLE_UART_REPL         (1)